Microbial profiling identifies potential key drivers in gastric cancer patients

Gastric cancer (GC) is the fifth most commonly diagnosed and third leading cause of cancer-related death in world. Microbiota believed to be associated with GC. Growing evidences showed Helicobacter pylori played a key role GC development. However, little was known about microbiota gastric juices tissues patients, thus it difficult understand other potential microbial causation for Here, we collected juice surgically removed from patients give insight into microbiota. Most microbes identified samples were opportunistic pathogens or resident flora human Further network analyses five as keystone species. H. direct GC, but might also function The tissue complex, some dominant contributed This study introduces juice, normal highlights functioned during